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102
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CSB
2003
IEEE
111views Bioinformatics» more  CSB 2003»
15 years 5 months ago
A Contradiction-Based Framework for Testing Gene Regulation Hypotheses
We have developed a mathematical framework for representing and testing hypotheses about gene, protein, and signaling molecule interactions. It takes a hierarchical, contradiction...
Steve Racunas, Nigam Shah, Nina V. Fedoroff
94
Voted
NAR
2010
111views more  NAR 2010»
14 years 7 months ago
Babelomics: an integrative platform for the analysis of transcriptomics, proteomics and genomic data with advanced functional pr
Babelomics is a response to the growing necessity of integrating and analyzing different types of genomic data in an environment that allows an easy functional interpretation of t...
Ignacio Medina, José Carbonell, Luis Pulido...
104
Voted
BMCBI
2006
120views more  BMCBI 2006»
15 years 16 days ago
A factor analysis model for functional genomics
Background: Expression array data are used to predict biological functions of uncharacterized genes by comparing their expression profiles to those of characterized genes. While b...
Rafal Kustra, Romy Shioda, Mu Zhu
100
Voted
BMCBI
2005
89views more  BMCBI 2005»
15 years 12 days ago
Theme discovery from gene lists for identification and viewing of multiple functional groups
Background: High throughput methods of the genome era produce vast amounts of data in the form of gene lists. These lists are large and difficult to interpret without advanced com...
Petri Pehkonen, Garry Wong, Petri Töröne...
BMCBI
2004
207views more  BMCBI 2004»
15 years 11 days ago
Computational identification of transcription factor binding sites by functional analysis of sets of genes sharing overrep-resen
Background: Transcriptional regulation is a key mechanism in the functioning of the cell, and is mostly effected through transcription factors binding to specific recognition moti...
Davide Corà, Ferdinando Di Cunto, Paolo Pro...