Background: Regulation of gene expression at the level of transcription is a major control point in many biological processes. Transcription factors (TFs) can activate and/or repr...
Paul J. Rushton, Marta T. Bokowiec, Thomas W. Laud...
Nonsmoothness pervades optimization, but the way it typically arises is highly structured. Nonsmooth behavior of an objective function is usually associated, locally, with an activ...
Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...
Since the advent of public data repositories for proteomics data, readily accessible results from high-throughput experiments have been accumulating steadily. Several large-scale p...
Sebastian Klie, Lennart Martens, Juan Antonio Vizc...
Besides being adopted as the new interchange format for the Internet, XML is finding increasing acceptance as a native data repository language. In order to make XML repositories ...