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» Analysis and prediction of antibacterial peptides
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ISMB
1998
14 years 11 months ago
Prediction of Signal Peptides and Signal Anchors by a Hidden Markov Model
A hidden Markov model of signal peptides has been developed. It contains submodels for the N-terminal part, the hydrophobic region, and the region around the cleavage site. For kn...
Henrik Nielsen, Anders Krogh
ICONIP
2008
14 years 11 months ago
Improved Mass Spectrometry Peak Intensity Prediction by Adaptive Feature Weighting
Mass spectrometry (MS) is a key technique for the analysis and identification of proteins. A prediction of spectrum peak intensities from pre computed molecular features would pave...
Alexandra Scherbart, Wiebke Timm, Sebastian Bö...
BMCBI
2010
191views more  BMCBI 2010»
14 years 4 months ago
Molecular dynamics simulation studies and in vitro site directed mutagenesis of avian beta-defensin Apl_AvBD2
Background: Defensins comprise a group of antimicrobial peptides, widely recognized as important elements of the innate immune system in both animals and plants. Cationicity, rath...
Soja Saghar Soman, Krishnankutty Chandrika Sivakum...
BMCBI
2010
127views more  BMCBI 2010»
14 years 9 months ago
PeptideMine - A webserver for the design of peptides for protein-peptide binding studies derived from protein-protein interactom
Background: Signal transduction events often involve transient, yet specific, interactions between structurally conserved protein domains and polypeptide sequences in target prote...
Khader Shameer, Lalima L. Madan, Shivamurthy Veera...
BMCBI
2010
106views more  BMCBI 2010»
14 years 9 months ago
Predicting MHC class I epitopes in large datasets
Background: Experimental screening of large sets of peptides with respect to their MHC binding capabilities is still very demanding due to the large number of possible peptide seq...
Kirsten Roomp, Iris Antes, Thomas Lengauer