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BMCBI
2006
76views more  BMCBI 2006»
15 years 5 months ago
Coloring the Mu transpososome
Background: Tangle analysis has been applied successfully to study proteins which bind two segments of DNA and can knot and link circular DNA. We show how tangle analysis can be e...
Isabel K. Darcy, Jeff Chang, Nathan Druivenga, Col...
BMCBI
2006
153views more  BMCBI 2006»
15 years 5 months ago
Intensity-based hierarchical Bayes method improves testing for differentially expressed genes in microarray experiments
Background: The small sample sizes often used for microarray experiments result in poor estimates of variance if each gene is considered independently. Yet accurately estimating v...
Maureen A. Sartor, Craig R. Tomlinson, Scott C. We...
BMCBI
2006
116views more  BMCBI 2006»
15 years 5 months ago
MICA: desktop software for comprehensive searching of DNA databases
Background: Molecular biologists work with DNA databases that often include entire genomes. A common requirement is to search a DNA database to find exact matches for a nondegener...
William A. Stokes, Benjamin S. Glick
BMCBI
2006
122views more  BMCBI 2006»
15 years 5 months ago
Computational reconstruction of transcriptional regulatory modules of the yeast cell cycle
Background: A transcriptional regulatory module (TRM) is a set of genes that is regulated by a common set of transcription factors (TFs). By organizing the genome into TRMs, a liv...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
CORR
2006
Springer
125views Education» more  CORR 2006»
15 years 4 months ago
Barriers and local minima in energy landscapes of stochastic local search
: A local search algorithm operating on an instance of a Boolean constraint satisfaction problem (in particular, k-SAT) can be viewed as a stochastic process traversing successive ...
Petteri Kaski
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