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PKDD
2004
Springer
113views Data Mining» more  PKDD 2004»
13 years 11 months ago
Discovery of Regulatory Connections in Microarray Data
Abstract. In this paper, we introduce a new approach for mining regulatory interactions between genes in microarray time series studies. A number of preprocessing steps transform t...
Michael Egmont-Petersen, Wim de Jonge, Arno Siebes
BMCBI
2011
12 years 9 months ago
A Simple Approach to Ranking Differentially Expressed Gene Expression Time Courses through Gaussian Process Regression
Background: The analysis of gene expression from time series underpins many biological studies. Two basic forms of analysis recur for data of this type: removing inactive (quiet) ...
Alfredo A. Kalaitzis, Neil D. Lawrence
BMCBI
2006
239views more  BMCBI 2006»
13 years 6 months ago
Applying dynamic Bayesian networks to perturbed gene expression data
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
Norbert Dojer, Anna Gambin, Andrzej Mizera, Bartek...
BMCBI
2007
173views more  BMCBI 2007»
13 years 6 months ago
Predicting state transitions in the transcriptome and metabolome using a linear dynamical system model
Background: Modelling of time series data should not be an approximation of input data profiles, but rather be able to detect and evaluate dynamical changes in the time series dat...
Ryoko Morioka, Shigehiko Kanaya, Masami Y. Hirai, ...
BMCBI
2007
198views more  BMCBI 2007»
13 years 6 months ago
Correlation analysis reveals the emergence of coherence in the gene expression dynamics following system perturbation
Time course gene expression experiments are a popular means to infer co-expression. Many methods have been proposed to cluster genes or to build networks based on similarity measu...
Nicola Neretti, Daniel Remondini, Marc Tatar, John...