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BMCBI
2008
128views more  BMCBI 2008»
15 years 2 months ago
Finding sequence motifs with Bayesian models incorporating positional information: an application to transcription factor bindin
Background: Biologically active sequence motifs often have positional preferences with respect to a genomic landmark. For example, many known transcription factor binding sites (T...
Nak-Kyeong Kim, Kannan Tharakaraman, Leonardo Mari...
BMCBI
2007
134views more  BMCBI 2007»
15 years 2 months ago
Efficient pairwise RNA structure prediction using probabilistic alignment constraints in Dynalign
Background: Joint alignment and secondary structure prediction of two RNA sequences can significantly improve the accuracy of the structural predictions. Methods addressing this p...
Arif Ozgun Harmanci, Gaurav Sharma, David H. Mathe...
BMCBI
2008
100views more  BMCBI 2008»
15 years 2 months ago
PatternLab for proteomics: a tool for differential shotgun proteomics
Background: A goal of proteomics is to distinguish between states of a biological system by identifying protein expression differences. Liu et al. demonstrated a method to perform...
Paulo C. Carvalho, Juliana S. G. Fischer, Emily I....
EM
2010
155views Management» more  EM 2010»
15 years 2 months ago
Hyperbolic Graphs of Small Complexity
In this paper we enumerate and classify the "simplest" pairs (M, G) where M is a closed orientable 3-manifold and G is a trivalent graph embedded in M. To enumerate the p...
Damian Heard, Craig Hodgson, Bruno Martelli, Carlo...
BMCBI
2006
108views more  BMCBI 2006»
15 years 2 months ago
RibAlign: a software tool and database for eubacterial phylogeny based on concatenated ribosomal protein subunits
Background: Until today, analysis of 16S ribosomal RNA (rRNA) sequences has been the de-facto gold standard for the assessment of phylogenetic relationships among prokaryotes. How...
Hanno Teeling, Frank Oliver Glöckner