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» Analysis of Variance for Gene Expression Microarray Data
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NIPS
2004
15 years 7 months ago
Probabilistic Inference of Alternative Splicing Events in Microarray Data
Alternative splicing (AS) is an important and frequent step in mammalian gene expression that allows a single gene to specify multiple products, and is crucial for the regulation ...
Ofer Shai, Brendan J. Frey, Quaid Morris, Qun Pan,...
NIPS
2003
15 years 7 months ago
Fast Feature Selection from Microarray Expression Data via Multiplicative Large Margin Algorithms
New feature selection algorithms for linear threshold functions are described which combine backward elimination with an adaptive regularization method. This makes them particular...
Claudio Gentile
BMCBI
2008
106views more  BMCBI 2008»
15 years 6 months ago
SpliceCenter: A suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi,
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
Michael C. Ryan, Barry Zeeberg, Natasha J. Caplen,...
BMCBI
2010
96views more  BMCBI 2010»
15 years 6 months ago
QTLminer: identifying genes regulating quantitative traits
Background: Quantitative trait locus (QTL) mapping identifies genomic regions that likely contain genes regulating a quantitative trait. However, QTL regions may encompass tens to...
Rudi Alberts, Klaus Schughart
BIBM
2009
IEEE
192views Bioinformatics» more  BIBM 2009»
16 years 1 months ago
A Multi-task Feature Selection Filter for Microarray Classification
A major challenge in microarray classification and biomarker discovery is dealing with small-sample high-dimensional data where the number of genes used as features is typically o...
Liang Lan, Slobodan Vucetic