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» Analysis of Variance for Gene Expression Microarray Data
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BIOINFORMATICS
2006
89views more  BIOINFORMATICS 2006»
15 years 1 months ago
Maximum significance clustering of oligonucleotide microarrays
Affymetrix high-density oligonucleotide microarrays measure expression of DNA transcripts using probesets, i.e. multiple probes per transcript. Usually, these multiple measurement...
Dick de Ridder, Frank J. T. Staal, Jacques J. M. v...
BMCBI
2010
84views more  BMCBI 2010»
15 years 1 months ago
Testing the additional predictive value of high-dimensional molecular data
Background: While high-dimensional molecular data such as microarray gene expression data have been used for disease outcome prediction or diagnosis purposes for about ten years i...
Anne-Laure Boulesteix, Torsten Hothorn
124
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BMCBI
2006
122views more  BMCBI 2006»
15 years 1 months ago
A multivariate prediction model for microarray cross-hybridization
Background: Expression microarray analysis is one of the most popular molecular diagnostic techniques in the post-genomic era. However, this technique faces the fundamental proble...
Yian A. Chen, Cheng-Chung Chou, Xinghua Lu, Elizab...
JCB
2007
198views more  JCB 2007»
15 years 1 months ago
Bayesian Hierarchical Model for Large-Scale Covariance Matrix Estimation
Many bioinformatics problems can implicitly depend on estimating large-scale covariance matrix. The traditional approaches tend to give rise to high variance and low accuracy esti...
Dongxiao Zhu, Alfred O. Hero III
BMCBI
2005
112views more  BMCBI 2005»
15 years 1 months ago
"Harshlighting" small blemishes on microarrays
Background: Microscopists are familiar with many blemishes that fluorescence images can have due to dust and debris, glass flaws, uneven distribution of fluids or surface coatings...
Mayte Suárez-Fariñas, Asifa Haider, ...