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BMCBI
2008
151views more  BMCBI 2008»
14 years 10 months ago
Application of the Linux cluster for exhaustive window haplotype analysis using the FBAT and Unphased programs
Background: Genetic association studies have been used to map disease-causing genes. A newly introduced statistical method, called exhaustive haplotype association study, analyzes...
Hiroyuki Mishima, Andrew C. Lidral, Jun Ni
75
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BMCBI
2010
124views more  BMCBI 2010»
14 years 10 months ago
GPFrontend and GPGraphics: graphical analysis tools for genetic association studies
Background: Most software packages for whole genome association studies are non-graphical, purely text based programs originally designed to run with UNIX-like operating systems. ...
Steffen Uebe, Francesca Pasutto, Mandy Krumbiegel,...
126
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BMCBI
2011
14 years 1 months ago
A hierarchical Bayesian network approach for linkage disequilibrium modeling and data-dimensionality reduction prior to genome-w
Background: Discovering the genetic basis of common genetic diseases in the human genome represents a public health issue. However, the dimensionality of the genetic data (up to 1...
Raphael Mourad, Christine Sinoquet, Philippe Leray
102
Voted
BMCBI
2010
151views more  BMCBI 2010»
14 years 10 months ago
CCRaVAT and QuTie - enabling analysis of rare variants in large-scale case control and quantitative trait association studies
Background: Genome-wide association studies have been successful in finding common variants influencing common traits. However, these associations only account for a fraction of t...
Robert Lawrence, Aaron G. Day-Williams, Katherine ...