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» Analysis of computational approaches for motif discovery
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DIS
2006
Springer
15 years 3 months ago
Prediction of Domain-Domain Interactions Using Inductive Logic Programming from Multiple Genome Databases
Protein domains are the building blocks of proteins, and their interactions are crucial in forming stable protein-protein interactions (PPI) and take part in many cellular processe...
Thanh Phuong Nguyen, Tu Bao Ho
RECOMB
2008
Springer
16 years 1 days ago
BayCis: A Bayesian Hierarchical HMM for Cis-Regulatory Module Decoding in Metazoan Genomes
The transcriptional regulatory sequences in metazoan genomes often consist of multiple cis-regulatory modules (CRMs). Each CRM contains locally enriched occurrences of binding site...
Tien-ho Lin, Pradipta Ray, Geir Kjetil Sandve, Sel...
RECOMB
2002
Springer
16 years 1 days ago
Monotony of surprise and large-scale quest for unusual words
The problem of characterizing and detecting recurrent sequence patterns such as substrings or motifs and related associations or rules is variously pursued in order to compress da...
Alberto Apostolico, Mary Ellen Bock, Stefano Lonar...
RECOMB
2006
Springer
16 years 1 days ago
Permutation Filtering: A Novel Concept for Significance Analysis of Large-Scale Genomic Data
Permutation of class labels is a common approach to build null distributions for significance analyis of microarray data. It is assumed to produce random score distributions, which...
Stefanie Scheid, Rainer Spang
BICOB
2010
Springer
14 years 12 months ago
Integrative Biomarker Discovery for Breast Cancer Metastasis from Gene Expression and Protein Interaction Data Using Error-toler
Biomarker discovery for complex diseases is a challenging problem. Most of the existing approaches identify individual genes as disease markers, thereby missing the interactions a...
Rohit Gupta, Smita Agrawal, Navneet Rao, Ze Tian, ...