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» Analysis of computational approaches for motif discovery
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BMCBI
2010
132views more  BMCBI 2010»
14 years 12 months ago
Protein network prediction and topological analysis in Leishmania major as a tool for drug target selection
Background: Leishmaniasis is a virulent parasitic infection that causes a worldwide disease burden. Most treatments have toxic side-effects and efficacy has decreased due to the e...
Andrés F. Flórez, Daeui Park, Jong B...
CHI
2008
ACM
16 years 4 days ago
Integrating statistics and visualization: case studies of gaining clarity during exploratory data analysis
Although both statistical methods and visualizations have been used by network analysts, exploratory data analysis remains a challenge. We propose that a tight integration of thes...
Adam Perer, Ben Shneiderman
BMCBI
2011
14 years 6 months ago
A novel approach to the clustering of microarray data via nonparametric density estimation
Background: Cluster analysis is a crucial tool in several biological and medical studies dealing with microarray data. Such studies pose challenging statistical problems due to di...
Riccardo De Bin, Davide Risso
RECOMB
2001
Springer
15 years 4 months ago
Extracting structural information using time-frequency analysis of protein NMR data
High-throughput, data-directed computational protocols for Structural Genomics (or Proteomics) are required in order to evaluate the protein products of genes for structure and fu...
Christopher James Langmead, Bruce Randall Donald
CRV
2005
IEEE
191views Robotics» more  CRV 2005»
15 years 5 months ago
Automated Behavioral Phenotype Detection and Analysis Using Color-Based Motion Tracking
The problem of elucidating the functional significance of genes is a key challenge of modern science. Solving this problem can lead to fundamental advancements across multiple are...
Alan Shimoide, Ilmi Yoon, Megumi Fuse, Holly C. Be...