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» Analysis of computational approaches for motif discovery
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BMCBI
2007
247views more  BMCBI 2007»
14 years 9 months ago
A survey of DNA motif finding algorithms
Background: Unraveling the mechanisms that regulate gene expression is a major challenge in biology. An important task in this challenge is to identify regulatory elements, especi...
Modan K. Das, Ho-Kwok Dai
TCS
2008
14 years 9 months ago
Motif patterns in 2D
Motif patterns consisting of sequences of intermixed solid and don't care characters have been introduced and studied in connection with pattern discovery problems of computa...
Alberto Apostolico, Laxmi Parida, Simona E. Rombo
BMCBI
2010
124views more  BMCBI 2010»
14 years 9 months ago
Estimation and efficient computation of the true probability of recurrence of short linear protein sequence motifs in unrelated
Background: Large datasets of protein interactions provide a rich resource for the discovery of Short Linear Motifs (SLiMs) that recur in unrelated proteins. However, existing met...
Norman E. Davey, Richard J. Edwards, Denis C. Shie...
BMCBI
2007
145views more  BMCBI 2007»
14 years 9 months ago
Improved benchmarks for computational motif discovery
Background: An important step in annotation of sequenced genomes is the identification of transcription factor binding sites. More than a hundred different computational methods h...
Geir Kjetil Sandve, Osman Abul, Vegard Walseng, Fi...
CIBCB
2006
IEEE
15 years 3 months ago
Motif Evaluation by Leave-one-out Scoring
Abstract— We propose a new method for collecting information on regulatory elements found by any motif discovery program. We suggest that combining the results of n leave-oneout ...
Audrey Girouard, Noah W. Smith, Donna K. Slonim