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» Analysis of variance components in gene expression data
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BMCBI
2008
124views more  BMCBI 2008»
14 years 10 months ago
Literature-aided meta-analysis of microarray data: a compendium study on muscle development and disease
Background: Comparative analysis of expression microarray studies is difficult due to the large influence of technical factors on experimental outcome. Still, the identified diffe...
Rob Jelier, Peter A. C. 't Hoen, Ellen Sterrenburg...
NAR
2008
174views more  NAR 2008»
14 years 8 months ago
miRGator: an integrated system for functional annotation of microRNAs
MicroRNAs (miRNAs) constitute an important class of regulators that are involved in various cellular and disease processes. However, the functional significance of each miRNA is m...
Seungyoon Nam, Bumjin Kim, Seokmin Shin, Sanghyuk ...
JMLR
2006
138views more  JMLR 2006»
14 years 10 months ago
Noisy-OR Component Analysis and its Application to Link Analysis
We develop a new component analysis framework, the Noisy-Or Component Analyzer (NOCA), that targets high-dimensional binary data. NOCA is a probabilistic latent variable model tha...
Tomás Singliar, Milos Hauskrecht
BMCBI
2010
172views more  BMCBI 2010»
14 years 10 months ago
Comparison of evolutionary algorithms in gene regulatory network model inference
Background: The evolution of high throughput technologies that measure gene expression levels has created a data base for inferring GRNs (a process also known as reverse engineeri...
Alina Sîrbu, Heather J. Ruskin, Martin Crane
NAR
1998
73views more  NAR 1998»
14 years 9 months ago
Identification and characterization of the RAD51 gene from the ciliate Tetrahymena thermophila
The RAD51 gene is a eukaryotic homolog of recA, a critical component in homologous recombination and DNA repair pathways in Escherichia coli. We have cloned the RAD51 homolog from...
Colin Campbell, Daniel P. Romero