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» Analysis of variance components in gene expression data
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BMCBI
2004
97views more  BMCBI 2004»
14 years 9 months ago
Calibration and assessment of channel-specific biases in microarray data with extended dynamical range
Background: Non-linearities in observed log-ratios of gene expressions, also known as intensity dependent log-ratios, can often be accounted for by global biases in the two channe...
Henrik Bengtsson, Göran Jönsson, Johan V...
BMCBI
2007
203views more  BMCBI 2007»
14 years 9 months ago
A Grid-based solution for management and analysis of microarrays in distributed experiments
Several systems have been presented in the last years in order to manage the complexity of large microarray experiments. Although good results have been achieved, most systems ten...
Ivan Porro, Livia Torterolo, Luca Corradi, Marco F...
BMCBI
2005
141views more  BMCBI 2005»
14 years 9 months ago
Construction and validation of the APOCHIP, a spotted oligo-microarray for the study of beta-cell apoptosis
Background: Type 1 diabetes mellitus (T1DM) is a autoimmune disease caused by a long-term negative balance between immune-mediated beta-cell damage and beta-cell repair/regenerati...
Nils E. Magnusson, Alessandra K. Cardozo, Mogens K...
BMCBI
2010
135views more  BMCBI 2010»
14 years 10 months ago
Delineation of amplification, hybridization and location effects in microarray data yields better-quality normalization
Background: Oligonucleotide arrays have become one of the most widely used high-throughput tools in biology. Due to their sensitivity to experimental conditions, normalization is ...
Marc Hulsman, Anouk Mentink, Eugene P. van Someren...
BMCBI
2005
131views more  BMCBI 2005»
14 years 9 months ago
Regularized Least Squares Cancer Classifiers from DNA microarray data
Background: The advent of the technology of DNA microarrays constitutes an epochal change in the classification and discovery of different types of cancer because the information ...
Nicola Ancona, Rosalia Maglietta, Annarita D'Addab...