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» Analysis of variance components in gene expression data
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BMCBI
2011
14 years 4 months ago
The dChip survival analysis module for microarray data
Background: Genome-wide expression signatures are emerging as potential marker for overall survival and disease recurrence risk as evidenced by recent commercialization of gene ex...
Samir B. Amin, Parantu K. Shah, Aimin Yan, Sophia ...
BMCBI
2010
106views more  BMCBI 2010»
14 years 9 months ago
Selection of optimal reference genes for normalization in quantitative RT-PCR
Background: Normalization in real-time qRT-PCR is necessary to compensate for experimental variation. A popular normalization strategy employs reference gene(s), which may introdu...
Inna Chervoneva, Yanyan Li, Stephanie Schulz, Sean...
BIBE
2003
IEEE
121views Bioinformatics» more  BIBE 2003»
15 years 3 months ago
Time Series Analysis of Gene Expression and Location Data
We develop a method for integrating time series expression profiles and factor-gene binding data to quantify dynamic aspects of gene regulation. We estimate latencies for transcr...
Chen-Hsiang Yeang, Tommi Jaakkola
BMEI
2008
IEEE
14 years 11 months ago
Clustering of High-Dimensional Gene Expression Data with Feature Filtering Methods and Diffusion Maps
The importance of gene expression data in cancer diagnosis and treatment by now has been widely recognized by cancer researchers in recent years. However, one of the major challen...
Rui Xu, Steven Damelin, Boaz Nadler, Donald C. Wun...
BMCBI
2007
128views more  BMCBI 2007»
14 years 9 months ago
Combining classifiers to predict gene function in Arabidopsis thaliana using large-scale gene expression measurements
Background: Arabidopsis thaliana is the model species of current plant genomic research with a genome size of 125 Mb and approximately 28,000 genes. The function of half of these ...
Hui Lan, Rachel Carson, Nicholas J. Provart, Antho...