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» Analysis of variance components in gene expression data
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BMCBI
2010
148views more  BMCBI 2010»
14 years 10 months ago
Applying unmixing to gene expression data for tumor phylogeny inference
Background: While in principle a seemingly infinite variety of combinations of mutations could result in tumor development, in practice it appears that most human cancers fall int...
Russell Schwartz, Stanley Shackney
GECCO
2007
Springer
162views Optimization» more  GECCO 2007»
15 years 4 months ago
A multi-objective approach to discover biclusters in microarray data
The main motivation for using a multi–objective evolutionary algorithm for finding biclusters in gene expression data is motivated by the fact that when looking for biclusters ...
Federico Divina, Jesús S. Aguilar-Ruiz
BMCBI
2005
223views more  BMCBI 2005»
14 years 9 months ago
Bioinformatics approaches for cross-species liver cancer analysis based on microarray gene expression profiling
Background: The completion of the sequencing of human, mouse and rat genomes and knowledge of cross-species gene homologies enables studies of differential gene expression in anim...
Hong Fang, Weida Tong, Roger Perkins, Leming M. Sh...
KES
2008
Springer
14 years 9 months ago
An Algorithm to Assess the Reliability of Hierarchical Clusters in Gene Expression Data
The validation of clusters discovered in bio-molecular data is a central issue in bioinformatics. Recently, stability-based methods have been successfully applied to the analysis o...
Roberto Avogadri, Matteo Brioschi, Francesca Ruffi...
BMCBI
2008
97views more  BMCBI 2008»
14 years 10 months ago
MCM-test: a fuzzy-set-theory-based approach to differential analysis of gene pathways
Background: Gene pathway can be defined as a group of genes that interact with each other to perform some biological processes. Along with the efforts to identify the individual g...
Lily R. Liang, Vinay Mandal, Yi Lu, Deepak Kumar