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BMCBI
2008
123views more  BMCBI 2008»
15 years 28 days ago
Statistical methodology for the analysis of dye-switch microarray experiments
Background: In individually dye-balanced microarray designs, each biological sample is hybridized on two different slides, once with Cy3 and once with Cy5. While this strategy ens...
Tristan Mary-Huard, Julie Aubert, Nadera Mansouri-...
106
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BMCBI
2008
150views more  BMCBI 2008»
15 years 28 days ago
13C labeling experiments at metabolic nonstationary conditions: An exploratory study
Background: Stimulus Response Experiments to unravel the regulatory properties of metabolic networks are becoming more and more popular. However, their ability to determine enzyme...
Sebastian Aljoscha Wahl, Katharina Nöh, Wolfg...
129
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BMCBI
2008
168views more  BMCBI 2008»
15 years 28 days ago
Predicting protein folding pathways at the mesoscopic level based on native interactions between secondary structure elements
Background: Since experimental determination of protein folding pathways remains difficult, computational techniques are often used to simulate protein folding. Most current techn...
Qingwu Yang, Sing-Hoi Sze
100
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DATAMINE
2008
143views more  DATAMINE 2008»
15 years 27 days ago
Automatically countering imbalance and its empirical relationship to cost
Learning from imbalanced datasets presents a convoluted problem both from the modeling and cost standpoints. In particular, when a class is of great interest but occurs relatively...
Nitesh V. Chawla, David A. Cieslak, Lawrence O. Ha...
107
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ECCC
2008
168views more  ECCC 2008»
15 years 27 days ago
Algebrization: A New Barrier in Complexity Theory
Any proof of P = NP will have to overcome two barriers: relativization and natural proofs. Yet over the last decade, we have seen circuit lower bounds (for example, that PP does n...
Scott Aaronson, Avi Wigderson
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