Background: The functional and structural characterisation of enzymes that belong to microbial metabolic pathways is very important for structure-based drug design. The main inter...
Helen A. Arcuri, Geraldo F. D. Zafalon, Evandro A....
Estimating an overall density function from repeated observations on each of a sample of independent subjects or experimental units is of interest. An example is provided by biodem...
Abstract--Independent vector analysis (IVA) is a method for separating convolutedly mixed signals that significantly reduces the occurrence of the well-known permutation problem in...
Alireza Masnadi-Shirazi, Wenyi Zhang, Bhaskar D. R...
Background: High-throughput functional genomics technologies generate large amount of data with hundreds or thousands of measurements per sample. The number of sample is usually m...
Cheng-Jian Xu, Huub C. J. Hoefsloot, Age K. Smilde
Background: The analysis of gene expression from time series underpins many biological studies. Two basic forms of analysis recur for data of this type: removing inactive (quiet) ...