Background: Designing maximally selective ligands that act on individual targets is the dominant paradigm in drug discovery. Poor selectivity can underlie toxicity and side effect...
We devise a boosting approach to classification and regression based on column generation using a mixture of kernels. Traditional kernel methods construct models based on a single...
— The size of data sets being collected and analyzed in the industry for business intelligence is growing rapidly, making traditional warehousing solutions prohibitively expensiv...
Ashish Thusoo, Joydeep Sen Sarma, Namit Jain, Zhen...
Background: Many bioinformatics analyses, ranging from gene clustering to phylogenetics, produce hierarchical trees as their main result. These are used to represent the relations...
The concept of dominance among nodes of a branch-decision tree, although known since a long time, is not exploited by general-purpose Mixed-Integer Linear Programming (MILP) enume...