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» Analyzing Large Spreadsheet Programs
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BMCBI
2011
14 years 4 months ago
A theoretical entropy score as a single value to express inhibitor selectivity
Background: Designing maximally selective ligands that act on individual targets is the dominant paradigm in drug discovery. Poor selectivity can underlie toxicity and side effect...
Joost C. M. Uitdehaag, Guido J. R. Zaman
KDD
2004
ACM
181views Data Mining» more  KDD 2004»
15 years 9 months ago
Column-generation boosting methods for mixture of kernels
We devise a boosting approach to classification and regression based on column generation using a mixture of kernels. Traditional kernel methods construct models based on a single...
Jinbo Bi, Tong Zhang, Kristin P. Bennett
ICDE
2010
IEEE
408views Database» more  ICDE 2010»
15 years 4 months ago
Hive - a petabyte scale data warehouse using Hadoop
— The size of data sets being collected and analyzed in the industry for business intelligence is growing rapidly, making traditional warehousing solutions prohibitively expensiv...
Ashish Thusoo, Joydeep Sen Sarma, Namit Jain, Zhen...
BMCBI
2010
143views more  BMCBI 2010»
14 years 9 months ago
ETE: a python Environment for Tree Exploration
Background: Many bioinformatics analyses, ranging from gene clustering to phylogenetics, produce hierarchical trees as their main result. These are used to represent the relations...
Jaime Huerta-Cepas, Joaquín Dopazo, Toni Ga...
INFORMS
2010
138views more  INFORMS 2010»
14 years 8 months ago
Pruning Moves
The concept of dominance among nodes of a branch-decision tree, although known since a long time, is not exploited by general-purpose Mixed-Integer Linear Programming (MILP) enume...
Matteo Fischetti, Domenico Salvagnin