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BMCBI
2005
99views more  BMCBI 2005»
14 years 11 months ago
CGH-Profiler: Data mining based on genomic aberration profiles
Background: CGH-Profiler is a program that supports the analysis of genomic aberrations measured by Comparative Genomic Hybridisation (CGH). Comparative genomic hybridisation (CGH...
Falk Schubert, Bernhard Tausch, Stefan Joos, Rolan...
BMCBI
2005
113views more  BMCBI 2005»
14 years 11 months ago
Pathway level analysis of gene expression using singular value decomposition
Background: A promising direction in the analysis of gene expression focuses on the changes in expression of specific predefined sets of genes that are known in advance to be rela...
John K. Tomfohr, Jun Lu, Thomas B. Kepler
BMCBI
2005
105views more  BMCBI 2005»
14 years 11 months ago
SNPHunter: a bioinformatic software for single nucleotide polymorphism data acquisition and management
Background: Single nucleotide polymorphisms (SNPs) provide an important tool in pinpointing susceptibility genes for complex diseases and in unveiling human molecular evolution. S...
Lin Wang, Simin Liu, Tianhua Niu, Xin Xu
BMCBI
2005
152views more  BMCBI 2005»
14 years 11 months ago
Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Markus Wistrand, Erik L. L. Sonnhammer
BMCBI
2004
200views more  BMCBI 2004»
14 years 11 months ago
ABC: software for interactive browsing of genomic multiple sequence alignment data
Background: Alignment and comparison of related genome sequences is a powerful method to identify regions likely to contain functional elements. Such analyses are data intensive, ...
Gregory M. Cooper, Senthil A. G. Singaravelu, Aren...