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BMCBI
2010
14 years 9 months ago
2010
Background: A growing demand for tools to assist the building and analysis of biological networks exists in systems biology. We argue that the use of a formal approach is relevant...
BMCBI
2007
14 years 9 months ago
2007
Background: Accurate identification of novel, functional noncoding (nc) RNA features in genome sequence has proven more difficult than for exons. Current algorithms identify and s...
BMCBI
2006
14 years 9 months ago
2006
Background: The imprint of natural selection on gene sequences is often difficult to detect. A plethora of methods have been devised to detect genetic changes due to selective pro...
BMCBI
2005
14 years 9 months ago
2005
Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
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BMCBI
2005
14 years 9 months ago
2005
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...