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BMCBI
2010
128views more  BMCBI 2010»
15 years 28 days ago
MPprimer: a program for reliable multiplex PCR primer design
Background: Multiplex PCR, defined as the simultaneous amplification of multiple regions of a DNA template or multiple DNA templates using more than one primer set (comprising a f...
Zhiyong Shen, Wubin Qu, Wen Wang, Yiming Lu, Yongh...
95
Voted
BMCBI
2010
111views more  BMCBI 2010»
15 years 28 days ago
Dynamic probe selection for studying microbial transcriptome with high-density genomic tiling microarrays
Background: Current commercial high-density oligonucleotide microarrays can hold millions of probe spots on a single microscopic glass slide and are ideal for studying the transcr...
Hedda Høvik, Tsute Chen
67
Voted
BMCBI
2010
65views more  BMCBI 2010»
15 years 28 days ago
VIPR: A probabilistic algorithm for analysis of microbial detection microarrays
Background: All infectious disease oriented clinical diagnostic assays in use today focus on detecting the presence of a single, well defined target agent or a set of agents. In r...
Adam F. Allred, Guang Wu, Tuya Wulan, Kael F. Fisc...
96
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BMCBI
2008
105views more  BMCBI 2008»
15 years 28 days ago
Novel computational methods for increasing PCR primer design effectiveness in directed sequencing
Background: Polymerase chain reaction (PCR) is used in directed sequencing for the discovery of novel polymorphisms. As the first step in PCR directed sequencing, effective PCR pr...
Kelvin Li, Anushka Brownley, Timothy B. Stockwell,...
107
Voted
BMCBI
2007
87views more  BMCBI 2007»
15 years 28 days ago
'Unite and conquer': enhanced prediction of protein subcellular localization by integrating multiple specialized tools
Background: Knowing the subcellular location of proteins provides clues to their function as well as the interconnectivity of biological processes. Dozens of tools are available f...
Yao Qing Shen, Gertraud Burger
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