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ICGA
1997
122views Optimization» more  ICGA 1997»
15 years 3 months ago
A Comparison of Global and Local Search Methods in Drug Docking
Molecular docking software makes computational predictions of the interaction of molecules. This can be useful, for example, in evaluating the binding of candidate drug molecules ...
Christopher D. Rosin, R. Scott Halliday, William E...
121
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SIGCOMM
2010
ACM
15 years 2 months ago
NapSAC: design and implementation of a power-proportional web cluster
Energy consumption is a major and costly problem in data centers. A large fraction of this energy goes to powering idle machines that are not doing any useful work. We identify tw...
Andrew Krioukov, Prashanth Mohan, Sara Alspaugh, L...
BMCBI
2010
105views more  BMCBI 2010»
15 years 2 months ago
A knowledge-guided strategy for improving the accuracy of scoring functions in binding affinity prediction
Background: Current scoring functions are not very successful in protein-ligand binding affinity prediction albeit their popularity in structure-based drug designs. Here, we propo...
Tiejun Cheng, Zhihai Liu, Renxiao Wang
146
Voted
PR
2008
228views more  PR 2008»
15 years 2 months ago
Accurate integration of multi-view range images using k-means clustering
3D modelling finds a wide range of applications in industry. However, due to the presence of surface scanning noise, accumulative registration errors, and improper data fusion, re...
Hong Zhou, Yonghuai Liu
142
Voted
BMCBI
2005
302views more  BMCBI 2005»
15 years 2 months ago
CGHPRO - A comprehensive data analysis tool for array CGH
Background: Array CGH (Comparative Genomic Hybridisation) is a molecular cytogenetic technique for the genome wide detection of chromosomal imbalances. It is based on the cohybrid...
Wei Chen, Fikret Erdogan, H.-Hilger Ropers, Steffe...
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