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ICML
2007
IEEE
15 years 10 months ago
An integrated approach to feature invention and model construction for drug activity prediction
We present a new machine learning approach for 3D-QSAR, the task of predicting binding affinities of molecules to target proteins based on 3D structure. Our approach predicts bind...
David Page, Jesse Davis, Soumya Ray, Vítor ...
BMCBI
2008
166views more  BMCBI 2008»
14 years 10 months ago
Biclustering via optimal re-ordering of data matrices in systems biology: rigorous methods and comparative studies
Background: The analysis of large-scale data sets via clustering techniques is utilized in a number of applications. Biclustering in particular has emerged as an important problem...
Peter A. DiMaggio Jr., Scott R. McAllister, Christ...
BMCBI
2011
14 years 1 months ago
Study of large and highly stratified population datasets by combining iterative pruning principal component analysis and STRUCTU
Background: The ever increasing sizes of population genetic datasets pose great challenges for population structure analysis. The Tracy-Widom (TW) statistical test is widely used ...
Tulaya Limpiti, Apichart Intarapanich, Anunchai As...
ESANN
2008
14 years 11 months ago
Learning to play Tetris applying reinforcement learning methods
In this paper the application of reinforcement learning to Tetris is investigated, particulary the idea of temporal difference learning is applied to estimate the state value funct...
Alexander Groß, Jan Friedland, Friedhelm Sch...
ML
2008
ACM
248views Machine Learning» more  ML 2008»
14 years 10 months ago
Feature selection via sensitivity analysis of SVM probabilistic outputs
Feature selection is an important aspect of solving data-mining and machine-learning problems. This paper proposes a feature-selection method for the Support Vector Machine (SVM) l...
Kai Quan Shen, Chong Jin Ong, Xiao Ping Li, Einar ...