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132
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BMCBI
2007
132views more  BMCBI 2007»
15 years 3 months ago
Dependence of paracentric inversion rate on tract length
Background: We develop a Bayesian method based on MCMC for estimating the relative rates of pericentric and paracentric inversions from marker data from two species. The method al...
Thomas L. York, Richard Durrett, Rasmus Nielsen
172
Voted
BMCBI
2007
147views more  BMCBI 2007»
15 years 3 months ago
Bias in random forest variable importance measures: Illustrations, sources and a solution
Variable importance measures for random forests have been receiving increased attention as a means of variable selection in many classification tasks in bioinformatics and relate...
Carolin Strobl, Anne-Laure Boulesteix, Achim Zeile...
BMCBI
2007
247views more  BMCBI 2007»
15 years 3 months ago
A survey of DNA motif finding algorithms
Background: Unraveling the mechanisms that regulate gene expression is a major challenge in biology. An important task in this challenge is to identify regulatory elements, especi...
Modan K. Das, Ho-Kwok Dai
147
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BMCBI
2007
128views more  BMCBI 2007»
15 years 3 months ago
A robust and efficient algorithm for the shape description of protein structures and its application in predicting ligand bindin
Background: An accurate description of protein shape derived from protein structure is necessary to establish an understanding of protein-ligand interactions, which in turn will l...
Lei Xie, Philip E. Bourne
158
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ESWA
2006
176views more  ESWA 2006»
15 years 3 months ago
Build grid-enabled large-scale collaboration environment in e-Learning grid
As a new branch of grid computing, e-Learning grid is emerging as a nationwide e-Learning infrastructure, which can provide innovative learning experience for learners. In such a ...
YuShun Li, ShengWen Yang, Jinlei Jiang, Meilin Shi
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