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BIOINFORMATICS
2011
12 years 10 months ago
A method for probing the mutational landscape of amyloid structure
Motivation: Proteins of all kinds can self-assemble into highly ordered β-sheet aggregates known as amyloid fibrils, important both biologically and clinically. However, the spe...
Charles W. O'Donnell, Jérôme Waldisp&...
BMCBI
2011
12 years 10 months ago
ShoRAH: estimating the genetic diversity of a mixed sample from next-generation sequencing data
Background: With next-generation sequencing technologies, experiments that were considered prohibitive only a few years ago are now possible. However, while these technologies hav...
Osvaldo Zagordi, Arnab Bhattacharya, Nicholas Erik...
AIME
2009
Springer
13 years 11 months ago
Prediction of Mechanical Lung Parameters Using Gaussian Process Models
Abstract. Mechanical ventilation can cause severe lung damage by inadequate adjustment of the ventilator. We introduce a Machine Learning approach to predict the pressure-dependent...
Steven Ganzert, Stefan Kramer, Knut Möller, D...