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BMCBI
2008
135views more  BMCBI 2008»
14 years 9 months ago
Knowledge-guided multi-scale independent component analysis for biomarker identification
Background: Many statistical methods have been proposed to identify disease biomarkers from gene expression profiles. However, from gene expression profile data alone, statistical...
Li Chen, Jianhua Xuan, Chen Wang, Ie-Ming Shih, Yu...
BMCBI
2010
176views more  BMCBI 2010»
14 years 9 months ago
Reverse engineering gene regulatory network from microarray data using linear time-variant model
nd: Gene regulatory network is an abstract mapping of gene regulations in living cells that can help to predict the system behavior of living organisms. Such prediction capability...
Mitra Kabir, Nasimul Noman, Hitoshi Iba
BMCBI
2007
162views more  BMCBI 2007»
14 years 9 months ago
Genome-wide identification of specific oligonucleotides using artificial neural network and computational genomic analysis
Background: Genome-wide identification of specific oligonucleotides (oligos) is a computationallyintensive task and is a requirement for designing microarray probes, primers, and ...
Chun-Chi Liu, Chin-Chung Lin, Ker-Chau Li, Wen-Shy...
BMCBI
2004
127views more  BMCBI 2004»
14 years 9 months ago
Optimized LOWESS normalization parameter selection for DNA microarray data
Background: Microarray data normalization is an important step for obtaining data that are reliable and usable for subsequent analysis. One of the most commonly utilized normaliza...
John A. Berger, Sampsa Hautaniemi, Anna-Kaarina J&...
BMCBI
2008
193views more  BMCBI 2008»
14 years 9 months ago
Missing value imputation for microarray gene expression data using histone acetylation information
Background: It is an important pre-processing step to accurately estimate missing values in microarray data, because complete datasets are required in numerous expression profile ...
Qian Xiang, Xianhua Dai, Yangyang Deng, Caisheng H...