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BMCBI
2006
183views more  BMCBI 2006»
14 years 9 months ago
Mining gene expression data by interpreting principal components
Background: There are many methods for analyzing microarray data that group together genes having similar patterns of expression over all conditions tested. However, in many insta...
Joseph C. Roden, Brandon W. King, Diane Trout, Ali...
JMLR
2010
136views more  JMLR 2010»
14 years 4 months ago
Evaluation Method for Feature Rankings and their Aggregations for Biomarker Discovery
In this paper we investigate the problem of evaluating ranked lists of biomarkers, which are typically an output of the analysis of high-throughput data. This can be a list of pro...
Ivica Slavkov, Bernard Zenko, Saso Dzeroski
CEC
2010
IEEE
14 years 11 months ago
An analysis of clustering objectives for feature selection applied to encrypted traffic identification
This work explores the use of clustering objectives in a Multi-Objective Genetic Algorithm (MOGA) for both, feature selection and cluster count optimization, under the application...
Carlos Bacquet, A. Nur Zincir-Heywood, Malcolm I. ...
BMCBI
2007
148views more  BMCBI 2007»
14 years 9 months ago
Computation of significance scores of unweighted Gene Set Enrichment Analyses
Background: Gene Set Enrichment Analysis (GSEA) is a computational method for the statistical evaluation of sorted lists of genes or proteins. Originally GSEA was developed for in...
Andreas Keller, Christina Backes, Hans-Peter Lenho...
BMCBI
2010
146views more  BMCBI 2010»
14 years 10 months ago
Genomic selection and complex trait prediction using a fast EM algorithm applied to genome-wide markers
Background: The information provided by dense genome-wide markers using high throughput technology is of considerable potential in human disease studies and livestock breeding pro...
Ross K. Shepherd, Theo H. E. Meuwissen, John A. Wo...