Background: There are many methods for analyzing microarray data that group together genes having similar patterns of expression over all conditions tested. However, in many insta...
Joseph C. Roden, Brandon W. King, Diane Trout, Ali...
In this paper we investigate the problem of evaluating ranked lists of biomarkers, which are typically an output of the analysis of high-throughput data. This can be a list of pro...
This work explores the use of clustering objectives in a Multi-Objective Genetic Algorithm (MOGA) for both, feature selection and cluster count optimization, under the application...
Carlos Bacquet, A. Nur Zincir-Heywood, Malcolm I. ...
Background: Gene Set Enrichment Analysis (GSEA) is a computational method for the statistical evaluation of sorted lists of genes or proteins. Originally GSEA was developed for in...
Andreas Keller, Christina Backes, Hans-Peter Lenho...
Background: The information provided by dense genome-wide markers using high throughput technology is of considerable potential in human disease studies and livestock breeding pro...
Ross K. Shepherd, Theo H. E. Meuwissen, John A. Wo...