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BMCBI
2010
154views more  BMCBI 2010»
15 years 5 months ago
Fine-tuning structural RNA alignments in the twilight zone
Background: A widely used method to find conserved secondary structure in RNA is to first construct a multiple sequence alignment, and then fold the alignment, optimizing a score ...
Andreas Bremges, Stefanie Schirmer, Robert Giegeri...
BMCBI
2007
153views more  BMCBI 2007»
15 years 5 months ago
Can Clustal-style progressive pairwise alignment of multiple sequences be used in RNA secondary structure prediction?
Background: In ribonucleic acid (RNA) molecules whose function depends on their final, folded three-dimensional shape (such as those in ribosomes or spliceosome complexes), the se...
Amelia B. Bellamy-Royds, Marcel Turcotte
BMCBI
2011
14 years 8 months ago
Study of large and highly stratified population datasets by combining iterative pruning principal component analysis and STRUCTU
Background: The ever increasing sizes of population genetic datasets pose great challenges for population structure analysis. The Tracy-Widom (TW) statistical test is widely used ...
Tulaya Limpiti, Apichart Intarapanich, Anunchai As...
JIB
2006
106views more  JIB 2006»
15 years 5 months ago
A structural keystone for drug design
3D-structures of proteins and potential ligands are the cornerstones of rational drug design. The first brick to build upon is selecting a protein target and finding out whether b...
Kristian Rother, Mathias Dunkel, Elke Michalsky, S...
ICC
2007
IEEE
15 years 11 months ago
New UWB Receiver Designs Based on a Gaussian-Laplacian Noise-Plus-MAI Model
—Two novel receiver structures which surpass the performance of the conventional matched filter receiver are proposed for ultra-wide bandwidth multiple access communications. Th...
Norman C. Beaulieu, Somasundaram Niranjayan