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BMCBI
2007
117views more  BMCBI 2007»
15 years 4 months ago
Supervised multivariate analysis of sequence groups to identify specificity determining residues
Background: Proteins that evolve from a common ancestor can change functionality over time, and it is important to be able identify residues that cause this change. In this paper ...
Iain M. Wallace, Desmond G. Higgins
BMCBI
2007
129views more  BMCBI 2007»
15 years 4 months ago
Exploring inconsistencies in genome-wide protein function annotations: a machine learning approach
Background: Incorrectly annotated sequence data are becoming more commonplace as databases increasingly rely on automated techniques for annotation. Hence, there is an urgent need...
Carson M. Andorf, Drena Dobbs, Vasant Honavar
CANDC
2006
ACM
15 years 3 months ago
Dealing with repetitions in sequencing by hybridization
DNA sequencing by hybridization (SBH) induces errors in the biochemical experiment. Some of them are random and disappear when the experiment is repeated. Others are systematic, i...
Jacek Blazewicz, Fred Glover, Marta Kasprzak, Wojc...
BMCBI
2007
130views more  BMCBI 2007»
15 years 3 months ago
Differential analysis for high density tiling microarray data
Background: High density oligonucleotide tiling arrays are an effective and powerful platform for conducting unbiased genome-wide studies. The ab initio probe selection method emp...
Srinka Ghosh, Heather A. Hirsch, Edward A. Sekinge...
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MLQ
2008
106views more  MLQ 2008»
15 years 3 months ago
A general Mitchell style iteration
We work out the details of a schema for a mixed support forcing iteration, which generalizes the Mitchell model [7] with no Aronszajn trees on 2. The main purpose of this paper is ...
John Krueger