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162
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BMCBI
2010
154views more  BMCBI 2010»
15 years 4 months ago
Binary image representation of a ligand binding site: its application to efficient sampling of a conformational ensemble
Background: Modelling the ligand binding site of a protein is an important component of understanding proteinligand interactions and is being actively studied. Even if the side ch...
Edon Sung, Sangsoo Kim, Whanchul Shin
DT
2006
98views more  DT 2006»
15 years 4 months ago
Handling variations and uncertainties
The widely used engineering decisions concerning the performance of technological equipment for process industries are usually deterministic. Since the early 1990s probabilistic m...
Tim Cheng
123
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ECCC
2007
86views more  ECCC 2007»
15 years 4 months ago
Testing Halfspaces
This paper addresses the problem of testing whether a Boolean-valued function f is a halfspace, i.e. a function of the form f(x) = sgn(w·x−θ). We consider halfspaces over the ...
Kevin Matulef, Ryan O'Donnell, Ronitt Rubinfeld, R...
BMCBI
2005
115views more  BMCBI 2005»
15 years 4 months ago
Statistical distributions of optimal global alignment scores of random protein sequences
Background: The inference of homology from statistically significant sequence similarity is a central issue in sequence alignments. So far the statistical distribution function un...
Hongxia Pang, Jiaowei Tang, Su-Shing Chen, Shiheng...
152
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TKDE
2008
171views more  TKDE 2008»
15 years 4 months ago
Efficient Similarity Search in Nonmetric Spaces with Local Constant Embedding
Similarity-based search has been a key factor for many applications such as multimedia retrieval, data mining, Web search and retrieval, and so on. There are two important issues r...
Lei Chen 0002, Xiang Lian
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