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» Approximation algorithms for projective clustering
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157
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BMCBI
2008
116views more  BMCBI 2008»
15 years 4 months ago
Clustering exact matches of pairwise sequence alignments by weighted linear regression
Background: At intermediate stages of genome assembly projects, when a number of contigs have been generated and their validity needs to be verified, it is desirable to align thes...
Alvaro J. González, Li Liao
159
Voted
STOC
2010
ACM
295views Algorithms» more  STOC 2010»
15 years 8 months ago
Approximation Schemes for Steiner Forest on Planar Graphs and Graphs of Bounded Treewidth
We give the first polynomial-time approximation scheme (PTAS) for the Steiner forest problem on planar graphs and, more generally, on graphs of bounded genus. As a first step, w...
MohammadHossein Bateni, MohammadTaghi Hajiaghayi a...
130
Voted
BMCBI
2007
128views more  BMCBI 2007»
15 years 3 months ago
Model order selection for bio-molecular data clustering
Background: Cluster analysis has been widely applied for investigating structure in bio-molecular data. A drawback of most clustering algorithms is that they cannot automatically ...
Alberto Bertoni, Giorgio Valentini
RECOMB
2009
Springer
15 years 10 months ago
Reconstructing Histories of Complex Gene Clusters on a Phylogeny
Abstract. Clusters of genes that have evolved by repeated segmental duplication present difficult challenges throughout genomic analysis, from sequence assembly to functional analy...
Tomás Vinar, Brona Brejová, Giltae S...
ITA
2006
167views Communications» more  ITA 2006»
15 years 3 months ago
Characterization of lung tumor subtypes through gene expression cluster validity assessment
The problem of assessing the reliability of clusters patients identified by clustering algorithms is crucial to estimate the significance of subclasses of diseases detectable at b...
Giorgio Valentini, Francesca Ruffino