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» Are There New Models of Computation
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99
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BMCBI
2010
119views more  BMCBI 2010»
15 years 24 days ago
Multi-task learning for cross-platform siRNA efficacy prediction: an in-silico study
Background: Gene silencing using exogenous small interfering RNAs (siRNAs) is now a widespread molecular tool for gene functional study and new-drug target identification. The key...
Qi Liu, Qian Xu, Vincent Wenchen Zheng, Hong Xue, ...
125
Voted
BMCBI
2007
159views more  BMCBI 2007»
15 years 24 days ago
sIR: siRNA Information Resource, a web-based tool for siRNA sequence design and analysis and an open access siRNA database
Background: RNA interference has revolutionized our ability to study the effects of altering the expression of single genes in mammalian (and other) cells through targeted knockdo...
Jyoti K. Shah, Harold R. Garner, Michael A. White,...
125
Voted
BMCBI
2006
122views more  BMCBI 2006»
15 years 22 days ago
PET-Tool: a software suite for comprehensive processing and managing of Paired-End diTag (PET) sequence data
Background: We recently developed the Paired End diTag (PET) strategy for efficient characterization of mammalian transcriptomes and genomes. The paired end nature of short PET se...
Kuo Ping Chiu, Chee-Hong Wong, Qiongyu Chen, Prami...
BMCBI
2006
110views more  BMCBI 2006»
15 years 22 days ago
CpGcluster: a distance-based algorithm for CpG-island detection
Background: Despite their involvement in the regulation of gene expression and their importance as genomic markers for promoter prediction, no objective standard exists for defini...
Michael Hackenberg, Christopher Previti, Pedro Lui...
75
Voted
GI
2005
Springer
15 years 6 months ago
Modellierung von Netzsicherheitsystemen umfangreicher vernetzter IT-Infrastrukturen
: Angesichts zunehmend komplexer werdender vernetzter IT-Infrastrukturen sind das integrierte Design und das automatisierte Management der unterschiedlichen Sicherheitstechniken un...
João Porto de Albuquerque, Heiko Krumm, Pau...
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