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104
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BMCBI
2011
14 years 1 months ago
ENGINES: exploring single nucleotide variation in entire human genomes
Background: Next generation ultra-sequencing technologies are starting to produce extensive quantities of data from entire human genome or exome sequences, and therefore new softw...
Jorge Amigo, Antonio Salas, Christopher Phillips
104
Voted
BMCBI
2011
14 years 1 months ago
Detection of recurrent rearrangement breakpoints from copy number data
Background: Copy number variants (CNVs), including deletions, amplifications, and other rearrangements, are common in human and cancer genomes. Copy number data from array compara...
Anna M. Ritz, Pamela L. Paris, Michael Ittmann, Co...
BMCBI
2011
14 years 1 months ago
ShoRAH: estimating the genetic diversity of a mixed sample from next-generation sequencing data
Background: With next-generation sequencing technologies, experiments that were considered prohibitive only a few years ago are now possible. However, while these technologies hav...
Osvaldo Zagordi, Arnab Bhattacharya, Nicholas Erik...
BMCBI
2011
14 years 1 months ago
BICEPP: an example-based statistical text mining method for predicting the binary characteristics of drugs
Background: The identification of drug characteristics is a clinically important task, but it requires much expert knowledge and consumes substantial resources. We have developed ...
Frank P. Y. Lin, Stephen Anthony, Thomas M. Polase...
98
Voted
BMCBI
2011
14 years 1 months ago
The Proteogenomic Mapping Tool
Background: High-throughput mass spectrometry (MS) proteomics data is increasingly being used to complement traditional structural genome annotation methods. To keep pace with the...
William S. Sanders, Nan Wang, Susan M. Bridges, Br...
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