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AO
2007
119views more  AO 2007»
14 years 9 months ago
The model of roles within an ontology development tool: Hozo
One of the major goals of ontology is to represent properly the underlying conceptual structure of the messy world reflecting the reality as much as possible. Ontology building to...
Riichiro Mizoguchi, Eiichi Sunagawa, Kouji Kozaki,...
BMCBI
2010
106views more  BMCBI 2010»
14 years 9 months ago
A computational evaluation of over-representation of regulatory motifs in the promoter regions of differentially expressed genes
Background: Observed co-expression of a group of genes is frequently attributed to co-regulation by shared transcription factors. This assumption has led to the hypothesis that pr...
Guofeng Meng, Axel Mosig, Martin Vingron
BMCBI
2010
131views more  BMCBI 2010»
14 years 9 months ago
A comparison of approximation techniques for variance-based sensitivity analysis of biochemical reaction systems
Background: Sensitivity analysis is an indispensable tool for the analysis of complex systems. In a recent paper, we have introduced a thermodynamically consistent variance-based ...
Hong-Xuan Zhang, John Goutsias
BMCBI
2007
86views more  BMCBI 2007»
14 years 9 months ago
Detecting microsatellites within genomes: significant variation among algorithms
Background: Microsatellites are short, tandemly-repeated DNA sequences which are widely distributed among genomes. Their structure, role and evolution can be analyzed based on exh...
Sébastien Leclercq, Eric Rivals, Philippe J...
BMCBI
2008
169views more  BMCBI 2008»
14 years 9 months ago
CompMoby: Comparative MobyDick for detection of cis-regulatory motifs
Background: The regulation of gene expression is complex and occurs at many levels, including transcriptional and post-transcriptional, in metazoans. Transcriptional regulation is...
Christina Chaivorapol, Collin Melton, Grace Wei, R...