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BMCBI
2004
144views more  BMCBI 2004»
13 years 6 months ago
GOtcha: a new method for prediction of protein function assessed by the annotation of seven genomes
Background: The function of a novel gene product is typically predicted by transitive assignment of annotation from similar sequences. We describe a novel method, GOtcha, for pred...
David M. A. Martin, Matthew Berriman, Geoffrey J. ...
HPDC
2010
IEEE
13 years 7 months ago
Modeling sequence and function similarity between proteins for protein functional annotation
A common task in biological research is to predict function for proteins by comparing sequences between proteins of known and unknown function. This is often done using pair-wise ...
Roger Higdon, Brenton Louie, Eugene Kolker
BMCBI
2005
143views more  BMCBI 2005»
13 years 6 months ago
Evaluation of BioCreAtIvE assessment of task 2
Background: Molecular Biology accumulated substantial amounts of data concerning functions of genes and proteins. Information relating to functional descriptions is generally extr...
Christian Blaschke, Eduardo Andrés Le&oacut...
GCB
2007
Springer
161views Biometrics» more  GCB 2007»
14 years 13 days ago
High-Precision Function Prediction using Conserved Interactions
: The recent availability of large data sets of protein- protein-interactions (PPIs) from various species offers new opportunities for functional genomics and proteomics. We descri...
Samira Jaeger, Ulf Leser
NAR
2007
90views more  NAR 2007»
13 years 5 months ago
The SUPERFAMILY database in 2007: families and functions
The SUPERFAMILY database provides protein domain assignments, at the SCOP ‘superfamily’ level, for the predicted protein sequences in over 400 completed genomes. A superfamily...
Derek Wilson, Martin Madera, Christine Vogel, Cyru...