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189
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BMCBI
2008
15 years 6 months ago
2008
Background: The traditional (unweighted) k-means is one of the most popular clustering methods for analyzing gene expression data. However, it suffers three major shortcomings. It...
199
Voted
BMCBI
2008
15 years 6 months ago
2008
Background: DNA methylation is an important epigenetic modification of the genome. Abnormal DNA methylation may result in silencing of tumor suppressor genes and is common in a va...
185
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BMCBI
2007
15 years 6 months ago
2007
Background: Lately, there has been a great interest in the application of information extraction methods to the biomedical domain, in particular, to the extraction of relationship...
181
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BMCBI
2007
15 years 6 months ago
2007
Background: There exist many segmentation techniques for genomic sequences, and the segmentations can also be based on many different biological features. We show how to evaluate ...
157
Voted
BMCBI
2008
15 years 6 months ago
2008
Background: In DNA microarray experiments, discovering groups of genes that share similar transcriptional characteristics is instrumental in functional annotation, tissue classifi...