82 search results - page 5 / 17 » Assigning genomic sequences to CATH |
BMCBI
2008
14 years 10 months ago
2008
Background: The current versions of the COG and arCOG databases, both excellent frameworks for studies in comparative and functional genomics, do not contain the nucleotide sequen...
BMCBI
2010
14 years 10 months ago
2010
Background: Recent developments of high-density SNP chips across a number of species require accurate genetic maps. Despite rapid advances in genome sequence assembly and availabi...
119
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BMCBI
2011
14 years 5 months ago
2011
Background: Computational analysis of metagenomes requires the taxonomical assignment of the genome contigs assembled from DNA reads of environmental samples. Because of the diver...
111
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BMCBI
2004
14 years 9 months ago
2004
Background: The function of a novel gene product is typically predicted by transitive assignment of annotation from similar sequences. We describe a novel method, GOtcha, for pred...
BMCBI
2007
14 years 10 months ago
2007
Background: Unsupervised annotation of proteins by software pipelines suffers from very high error rates. Spurious functional assignments are usually caused by unwarranted homolog...