Systems pharmacology is an emergent area that studies drug action across multiple scales of complexity, from molecular and cellular to tissue and organism levels. There is a criti...
Olivier Taboureau, Sonny Kim Nielsen, Karine Audou...
The UCSC Cancer Genomics Browser (https:// genome-cancer.ucsc.edu) comprises a suite of web-based tools to integrate, visualize and analyze cancer genomics and clinical data. The ...
J. Zachary Sanborn, Stephen C. Benz, Brian Craft, ...
Cancer is known to have abundant copy number alterations (CNAs) that greatly contribute to its pathogenesis and progression. Investigation of CNA regions could potentially help id...
Qingyi Cao, Meng Zhou, Xujun Wang, Clifford A. Mey...
The initiation and regulation of transcription in eukaryotes is complex and involves a large number of transcription factors (TFs), which are known to bind to the regulatory regio...
Ulf Schaefer, Sebastian Schmeier, Vladimir B. Baji...
Several molecular systems form large-scale objects. One would like to understand their assembly and how this assembly is regulated. As a first step, we investigate the phase trans...