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» Associative Omega-product of Processes
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BMCBI
2007
145views more  BMCBI 2007»
15 years 2 months ago
Genome bioinformatic analysis of nonsynonymous SNPs
Background: Genome-wide association studies of common diseases for common, low penetrance causal variants are underway. A proportion of these will alter protein sequences, the mos...
David F. Burke, Catherine L. Worth, Eva-Maria Prie...
BMCBI
2007
160views more  BMCBI 2007»
15 years 2 months ago
Identifying protein complexes directly from high-throughput TAP data with Markov random fields
Background: Predicting protein complexes from experimental data remains a challenge due to limited resolution and stochastic errors of high-throughput methods. Current algorithms ...
Wasinee Rungsarityotin, Roland Krause, Arno Sch&ou...
BMCBI
2008
94views more  BMCBI 2008»
15 years 2 months ago
Conserved co-expression for candidate disease gene prioritization
Background: Genes that are co-expressed tend to be involved in the same biological process. However, co-expression is not a very reliable predictor of functional links between gen...
Martin Oti, Jeroen van Reeuwijk, Martijn A. Huynen...
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BMCBI
2008
173views more  BMCBI 2008»
15 years 2 months ago
Improved machine learning method for analysis of gas phase chemistry of peptides
Background: Accurate peptide identification is important to high-throughput proteomics analyses that use mass spectrometry. Search programs compare fragmentation spectra (MS/MS) o...
Allison Gehrke, Shaojun Sun, Lukasz A. Kurgan, Nat...
BMCBI
2007
130views more  BMCBI 2007»
15 years 2 months ago
Requirements and ontology for a G protein-coupled receptor oligomerization knowledge base
Background: G Protein-Coupled Receptors (GPCRs) are a large and diverse family of membrane proteins whose members participate in the regulation of most cellular and physiological ...
Lucy Skrabanek, Marta Murcia, Michel Bouvier, Laks...