Sciweavers

188 search results - page 21 / 38
» Automated functional classification of experimental and pred...
Sort
View
BMCBI
2010
123views more  BMCBI 2010»
14 years 12 months ago
A new protein binding pocket similarity measure based on comparison of clouds of atoms in 3D: application to ligand prediction
Background: Predicting which molecules can bind to a given binding site of a protein with known 3D structure is important to decipher the protein function, and useful in drug desi...
Brice Hoffmann, Mikhail Zaslavskiy, Jean-Philippe ...
RECOMB
2001
Springer
16 years 4 days ago
Towards predicting coiled-coil protein interactions
Protein-protein interactions play a central role in many cellular functions, and as whole-genome data accumulates, computational methods for predicting these interactions become i...
Mona Singh, Peter S. Kim
BMCBI
2005
116views more  BMCBI 2005»
14 years 11 months ago
SuperLigands - a database of ligand structures derived from the Protein Data Bank
Background: Currently, the PDB contains approximately 29,000 protein structures comprising over 70,000 experimentally determined three-dimensional structures of over 5,000 differe...
Elke Michalsky, Mathias Dunkel, Andrean Goede, Rob...
BMCBI
2011
14 years 3 months ago
GPCR-SSFE: A comprehensive database of G-protein-coupled receptor template predictions and homology models
Background: G protein-coupled receptors (GPCRs) transduce a wide variety of extracellular signals to within the cell and therefore have a key role in regulating cell activity and ...
Catherine L. Worth, Annika Kreuchwig, Gunnar Klein...
IJBRA
2008
63views more  IJBRA 2008»
14 years 12 months ago
Protein cavity clustering based on community structure of pocket similarity network
: Functions of a protein are mainly determined by its structure. Surface cavities, also called pockets or clefts, are ordinarily regarded as potentially active sites where the prot...
Zhi-Ping Liu, Ling-Yun Wu, Yong Wang, Xiang-Sun Zh...