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BMCBI
2008
14 years 9 months ago
2008
Background: Systematic approaches for identifying proteins involved in different types of cancer are needed. Experimental techniques such as microarrays are being used to characte...
BIOINFORMATICS
2007
14 years 9 months ago
2007
Motivation: Protein–protein complexes are known to play key roles in many cellular processes. However, they are often not accessible to experimental study because of their low s...
BMCBI
2008
14 years 9 months ago
2008
Background: T-cell epitopes that promiscuously bind to multiple alleles of a human leukocyte antigen (HLA) supertype are prime targets for development of vaccines and immunotherap...
BMCBI
2007
14 years 9 months ago
2007
Background: The structure annotation of a genome is based either on ab initio methodologies or on similaritiy searches versus molecules that have been already annotated. Ab initio...
BMCBI
2007
14 years 9 months ago
2007
Background: In structural genomics, an important goal is the detection and classification of protein–protein interactions, given the structures of the interacting partners. We h...