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BMCBI
2007
96views more  BMCBI 2007»
14 years 9 months ago
Protein subcellular localization prediction based on compartment-specific features and structure conservation
Motivation: Protein subcellular localization is crucial for genome annotation, protein function prediction, and drug discovery. However, since determining subcellular localization...
Emily Chia-Yu Su, Hua-Sheng Chiu, Allan Lo, Jenn-K...
BMCBI
2007
129views more  BMCBI 2007»
14 years 9 months ago
Exploring inconsistencies in genome-wide protein function annotations: a machine learning approach
Background: Incorrectly annotated sequence data are becoming more commonplace as databases increasingly rely on automated techniques for annotation. Hence, there is an urgent need...
Carson M. Andorf, Drena Dobbs, Vasant Honavar
CSB
2004
IEEE
146views Bioinformatics» more  CSB 2004»
15 years 1 months ago
Automated Protein Classification Using Consensus Decision
We propose a novel technique for automatically generating the SCOP classification of a protein structure with high accuracy. High accuracy is achieved by combining the decisions o...
Tolga Can, Orhan Çamoglu, Ambuj K. Singh, Y...
BMCBI
2010
153views more  BMCBI 2010»
14 years 9 months ago
Analysis of substructural variation in families of enzymatic proteins with applications to protein function prediction
Background: Structural variations caused by a wide range of physico-chemical and biological sources directly influence the function of a protein. For enzymatic proteins, the struc...
Drew H. Bryant, Mark Moll, Brian Y. Chen, Viachesl...
BIOINFORMATICS
2000
149views more  BIOINFORMATICS 2000»
14 years 9 months ago
MaxSub: an automated measure for the assessment of protein structure prediction quality
Motivation: Evaluating the accuracy of predicted models is critical for assessing structure prediction methods. Because this problem is not trivial, a large number of different as...
Naomi Siew, Arne Elofsson, Leszek Rychlewski, Dani...