Inferring orthologous and paralogous genes is an important problem in whole genomes comparisons, both for functional or evolutionary studies. In this paper, we introduce a new appr...
Background: Protein remote homology detection is a central problem in computational biology. Most recent methods train support vector machines to discriminate between related and ...
—Automated estimation of DNA base-sequences is an important step in genomics and in many other emerging fields in biological and medical sciences. Current automated sequencers p...
Xiaomeng Shi, Desmond S. Lun, Jim Meldrim, Ralf K&...
In this paper, we argue that KBS validation should not be limited to testing functional properties of the system, such as its input - output behavior, but must also address its dy...
The avMlability of large EST(Expressed Sequence Tag)databases has led to a revolution in the waynew genes are cloned. Difficulties arise, however,due to high error rates and redun...