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GECCO
2005
Springer
162views Optimization» more  GECCO 2005»
15 years 2 months ago
Discovering biological motifs with genetic programming
Choosing the right representation for a problem is important. In this article we introduce a linear genetic programming approach for motif discovery in protein families, and we al...
Rolv Seehuus, Amund Tveit, Ole Edsberg
ISMB
1997
14 years 10 months ago
Identifying Chimerism in Proteins Using Hidden Markov Models of Codon Usage
Protein chimerism is a phenomenon involving the combination of multiple ancestral sequences into a single, multi-domain protein through evolution. We propose a novel method for de...
Lawrence Hunter, Barry Zeeberg
BMCBI
2005
134views more  BMCBI 2005»
14 years 9 months ago
Ancestral sequence alignment under optimal conditions
Background: Multiple genome alignment is an important problem in bioinformatics. An important subproblem used by many multiple alignment approaches is that of aligning two multipl...
Alexander K. Hudek, Daniel G. Brown 0001
BMCBI
2011
14 years 1 months ago
A Novel And Well-Defined Benchmarking Method For Second Generation Read Mapping
Background: Second generation sequencing technologies yield DNA sequence data at ultra high-throughput. Common to most biological applications is a mapping of the reads to an almo...
Manuel Holtgrewe, Anne-Katrin Emde, David Weese, K...
CDC
2008
IEEE
125views Control Systems» more  CDC 2008»
15 years 3 months ago
Dynamical structure analysis of sparsity and minimality heuristics for reconstruction of biochemical networks
— Network reconstruction, i.e. obtaining network structure from input-output information, is a central theme in systems biology. A variety of approaches aim to obtaining structur...
Russell Howes, Lee John Eccleston, Jorge M. Goncal...