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BMCBI
2008
148views more  BMCBI 2008»
15 years 4 months ago
Discovering biclusters in gene expression data based on high-dimensional linear geometries
Background: In DNA microarray experiments, discovering groups of genes that share similar transcriptional characteristics is instrumental in functional annotation, tissue classifi...
Xiangchao Gan, Alan Wee-Chung Liew, Hong Yan
EC
2010
157views ECommerce» more  EC 2010»
15 years 4 months ago
Memetic Algorithms for Continuous Optimisation Based on Local Search Chains
Memetic algorithms with continuous local search methods have arisen as effective tools to address the difficulty of obtaining reliable solutions of high precision for complex cont...
Daniel Molina, Manuel Lozano, Carlos García...
BMCBI
2006
137views more  BMCBI 2006»
15 years 4 months ago
A classification-based framework for predicting and analyzing gene regulatory response
Background: We have recently introduced a predictive framework for studying gene transcriptional regulation in simpler organisms using a novel supervised learning algorithm called...
Anshul Kundaje, Manuel Middendorf, Mihir Shah, Chr...
BMCBI
2006
128views more  BMCBI 2006»
15 years 4 months ago
Model-driven user interfaces for bioinformatics data resources: regenerating the wheel as an alternative to reinventing it
Background: The proliferation of data repositories in bioinformatics has resulted in the development of numerous interfaces that allow scientists to browse, search and analyse the...
Kevin L. Garwood, Christopher Garwood, Cornelia He...
BMCBI
2007
113views more  BMCBI 2007»
15 years 4 months ago
Statistical power of phylo-HMM for evolutionarily conserved element detection
Background: An important goal of comparative genomics is the identification of functional elements through conservation analysis. Phylo-HMM was recently introduced to detect conse...
Xiaodan Fan, Jun Zhu, Eric E. Schadt, Jun S. Liu
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