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109
Voted
BMCBI
2010
110views more  BMCBI 2010»
15 years 24 days ago
GenHtr: a tool for comparative assessment of genetic heterogeneity in microbial genomes generated by massive short-read sequenci
Background: Microevolution is the study of short-term changes of alleles within a population and their effects on the phenotype of organisms. The result of the below-species-level...
GongXin Yu
BMCBI
2007
107views more  BMCBI 2007»
15 years 24 days ago
Reuse of structural domain-domain interactions in protein networks
Background: Protein interactions are thought to be largely mediated by interactions between structural domains. Databases such as iPfam relate interactions in protein structures t...
Benjamin Schuster-Böckler, Alex Bateman
103
Voted
BMCBI
2008
125views more  BMCBI 2008»
15 years 24 days ago
SynteBase/SynteView: a tool to visualize gene order conservation in prokaryotic genomes
Background: It has been repeatedly observed that gene order is rapidly lost in prokaryotic genomes. However, persistent synteny blocks are found when comparing more or less distan...
Frédéric Lemoine, Bernard Labedan, O...
109
Voted
BMCBI
2006
166views more  BMCBI 2006»
15 years 22 days ago
Extraction of phylogenetic network modules from the metabolic network
Background: In bio-systems, genes, proteins and compounds are related to each other, thus forming complex networks. Although each organism has its individual network, some organis...
Takuji Yamada, Minoru Kanehisa, Susumu Goto
109
Voted
CORR
2007
Springer
122views Education» more  CORR 2007»
15 years 19 days ago
Social Media as Windows on the Social Life of the Mind
This is a programmatic paper, marking out two directions in which the study of social media can contribute to broader problems of social science: understanding cultural evolution ...
Cosma Rohilla Shalizi