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BIOINFORMATICS
2006
101views more  BIOINFORMATICS 2006»
14 years 9 months ago
A lock-and-key model for protein-protein interactions
Motivation: Protein-protein interaction networks are one of the major post-genomic data sources available to molecular biologists. They provide a comprehensive view of the global ...
Julie L. Morrison, Rainer Breitling, Desmond J. Hi...
BMCBI
2008
100views more  BMCBI 2008»
14 years 9 months ago
Extracting unrecognized gene relationships from the biomedical literature via matrix factorizations
Background: The construction of literature-based networks of gene-gene interactions is one of the most important applications of text mining in bioinformatics. Extracting potentia...
Hyunsoo Kim, Haesun Park, Barry L. Drake
BMCBI
2008
134views more  BMCBI 2008»
14 years 9 months ago
Identification of transcription factor contexts in literature using machine learning approaches
Background: Availability of information about transcription factors (TFs) is crucial for genome biology, as TFs play a central role in the regulation of gene expression. While man...
Hui Yang, Goran Nenadic, John A. Keane
BMCBI
2010
164views more  BMCBI 2010»
14 years 9 months ago
Investigating the validity of current network analysis on static conglomerate networks by protein network stratification
Background: A molecular network perspective forms the foundation of systems biology. A common practice in analyzing protein-protein interaction (PPI) networks is to perform networ...
Minlu Zhang, Long J. Lu
BMCBI
2008
144views more  BMCBI 2008»
14 years 9 months ago
Rule-based knowledge aggregation for large-scale protein sequence analysis of influenza A viruses
Background: The explosive growth of biological data provides opportunities for new statistical and comparative analyses of large information sets, such as alignments comprising te...
Olivo Miotto, Tin Wee Tan, Vladimir Brusic