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» Automatic Generation of Sigma-Protocols
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BMCBI
2010
118views more  BMCBI 2010»
14 years 12 months ago
Computing H/D-Exchange rates of single residues from data of proteolytic fragments
Background: Protein conformation and protein/protein interaction can be elucidated by solution-phase Hydrogen/ Deuterium exchange (sHDX) coupled to high-resolution mass analysis o...
Ernst Althaus, Stefan Canzar, Carsten Ehrler, Mark...
BMCBI
2008
130views more  BMCBI 2008»
14 years 12 months ago
A novel series of compositionally biased substitution matrices for comparing Plasmodium proteins
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
Kevin Brick, Elisabetta Pizzi
99
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BMCBI
2007
145views more  BMCBI 2007»
14 years 12 months ago
Colony size measurement of the yeast gene deletion strains for functional genomics
Background: Numerous functional genomics approaches have been developed to study the model organism yeast, Saccharomyces cerevisiae, with the aim of systematically understanding t...
Negar Memarian, Matthew Jessulat, Javad Alirezaie,...
84
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BMCBI
2008
114views more  BMCBI 2008»
14 years 12 months ago
Visualizing and clustering high throughput sub-cellular localization imaging
Background: The expansion of automatic imaging technologies has created a need to be able to efficiently compare and review large sets of image data. To enable comparisons of imag...
Nicholas A. Hamilton, Rohan D. Teasdale
BMCBI
2007
136views more  BMCBI 2007»
14 years 12 months ago
Reduced modeling of signal transduction - a modular approach
Background: Combinatorial complexity is a challenging problem in detailed and mechanistic mathematical modeling of signal transduction. This subject has been discussed intensively...
Markus Koschorreck, Holger Conzelmann, Sybille Ebe...