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BMCBI
2007
181views more  BMCBI 2007»
14 years 12 months ago
Genes2Networks: connecting lists of gene symbols using mammalian protein interactions databases
Background: In recent years, mammalian protein-protein interaction network databases have been developed. The interactions in these databases are either extracted manually from lo...
Seth I. Berger, Jeremy M. Posner, Avi Ma'ayan
BMCBI
2007
145views more  BMCBI 2007»
14 years 12 months ago
Genome bioinformatic analysis of nonsynonymous SNPs
Background: Genome-wide association studies of common diseases for common, low penetrance causal variants are underway. A proportion of these will alter protein sequences, the mos...
David F. Burke, Catherine L. Worth, Eva-Maria Prie...
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BMCBI
2008
145views more  BMCBI 2008»
14 years 12 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
BMCBI
2007
116views more  BMCBI 2007»
14 years 12 months ago
primetv: a viewer for reconciled trees
Background: Evolutionary processes, such as gene family evolution or parasite-host cospeciation, can often be viewed as a tree evolving inside another tree. Relating two given tre...
Bengt Sennblad, Eva Schreil, Ann-Charlotte Berglun...
BMCBI
2008
147views more  BMCBI 2008»
14 years 12 months ago
Assessment of disease named entity recognition on a corpus of annotated sentences
Background: In recent years, the recognition of semantic types from the biomedical scientific literature has been focused on named entities like protein and gene names (PGNs) and ...
Antonio Jimeno-Yepes, Ernesto Jiménez-Ruiz,...